https://ghrieb.r-universe.devRecent package updates in ghriebR-universehttps://github.com/ghrieb.pnghttps://ghrieb.r-universe.devThu, 01 Oct 2026 13:05:47 GMTghriebabdelkarimhani@gmail.com (Abdelkarim Hani Ghrieb)Orchestrates the statistical pipeline underlying prognostic biomarker discovery from bulk RNA-seq SummarizedExperiment objects: sample-identity and quality-control auditing, confounder and design-formula detection prior to differential expression, signature construction with explicit cross-validation stability reporting, survival modeling (Kaplan-Meier, log-rank, Cox proportional hazards), and external validation against public cohorts. Every automated statistical decision is reported with its supporting statistic and a plain-language rationale, and validation stages are gated rather than silently degraded when guardrail criteria are not met. The package records all guardrail decisions, flag ledgers, and validation results in a structured audit trail that can be rendered into a standalone HTML report.https://github.com/r-universe/bioc/actions/runs/37042390509Thu, 01 Oct 2026 13:05:47 GMTrnaSentry0.99.19successhttps://bioc.r-universe.devhttps://github.com/bioc/rnaSentryrnaSentry.RmdrnaSentry.htmlIntroduction to rnaSentry 2026-08-03 01:17:472026-10-01 01:19:47getting-started.Rmdgetting-started.htmlGetting started: from two CSVs to a SummarizedExperiment 2026-08-05 17:22:282026-09-30 21:57:23case-study-impact.Rmdcase-study-impact.htmlNaive analysis vs rnaSentry: what the guardrails prevent 2026-08-05 16:18:552026-09-30 23:02:06case-study-brca.Rmdcase-study-brca.htmlCase study: breast cancer (GSE20685) 2026-08-04 20:32:272026-09-30 23:02:06case-study-confounder-audit.Rmdcase-study-confounder-audit.htmlCase study: confounder audit 2026-08-04 20:32:272026-09-10 22:17:48case-study-small-cohort.Rmdcase-study-small-cohort.htmlCase study: small cohorts 2026-08-04 20:32:272026-09-09 18:16:09